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Redesigned Hepatitis C Drug Becomes a Powerful New Treatment for COVID-19 Scientists transformed an old drug into a potent COVID-19 treatment effective against drug-resistant variants.
Protecting Against Large Damaging Energy Bursts in Fusion Energy Devices Scientists found a potential way to suppress large damaging edge-localized modes, providing an approach to protect future devices.
A Standout Solvent for Today’s Biorefineries Researchers identify butylamine as a promising solution to many challenges at biorefineries.
Exploring the Potential of a Formate-Based Bioeconomy Researchers demonstrated an efficient strain of bacteria for bioproduction that grows on the promising feedstock formate.

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Illustration of an undulator’s magnetic field being manipulated to generate ultrafast X-ray pulses. The illustration compares the process to music: Instead of individual notes, researchers played a full melody.

Demonstrating Unprecedented Control of X-ray Pulses

Read more about Demonstrating Unprecedented Control of X-ray Pulses

X-ray map of molecular carbonate acquired using scanning transmission X-ray microscopy (yellow). It is overlaid on an inverted bright-field transmission electron microscopy image.

Bennu’s Ancient Brine Sheds Light on Recipe for Life

Read more about Bennu’s Ancient Brine Sheds Light on Recipe for Life

The Uncertainty Toolbox provides a suite of evaluation, visualization, and recalibration functionalities for uncertainty quantification.

Uncertainty Toolbox: A Software Toolbox for Quantifying Uncertainty and More

Read more about Uncertainty Toolbox: A Software Toolbox for Quantifying Uncertainty and More

Images showing mice injected with radioactive antimony. Left panel with TREN-CAM shows how the radioactive antimony will be active longer in the treatment areas. The right panel shows that the antimony without TREN-CAM doesn’t stay in the desired areas.

Progress Towards Unlocking Antimony’s Cancer Treatment Potential

Read more about Progress Towards Unlocking Antimony’s Cancer Treatment Potential

Latest Highlights

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Illustration of an undulator’s magnetic field being manipulated to generate ultrafast X-ray pulses. The illustration compares the process to music: Instead of individual notes, researchers played a full melody.

Demonstrating Unprecedented Control of X-ray Pulses

Researchers have used an undulator’s magnetic field to generate and control ultrafast X-ray pulses.

X-ray map of molecular carbonate acquired using scanning transmission X-ray microscopy (yellow). It is overlaid on an inverted bright-field transmission electron microscopy image.

Bennu’s Ancient Brine Sheds Light on Recipe for Life

Using the Advanced Light Source and Molecular Foundry, researchers identified the chemical stew found in samples of the asteroid Bennu.

Images showing mice injected with radioactive antimony. Left panel with TREN-CAM shows how the radioactive antimony will be active longer in the treatment areas. The right panel shows that the antimony without TREN-CAM doesn’t stay in the desired areas.

Progress Towards Unlocking Antimony’s Cancer Treatment Potential

Researchers gain a new understanding of the binding chemistry of radioactive antimony, opening doors for targeted therapy.

Scientists used a new method to create 3D metallic and semiconductor nanostructures. The scale bar represents one micrometer. The graphics show how the researchers combined multiple techniques to layer materials on top of a 3D DNA framework "scaffolding."

Building 3D Nanoscale Structures Through DNA-Assembly and Templating

Using DNA scaffolding, scientists developed a universal method for producing a wide variety of functional, 3D metallic and semiconductor nanostructures

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The Uncertainty Toolbox provides a suite of evaluation, visualization, and recalibration functionalities for uncertainty quantification.

Uncertainty Toolbox: A Software Toolbox for Quantifying Uncertainty and More

ORNL’s Frontier supercomputer earned the top ranking on the TOP500 list in June 2022, marking it as the world’s fastest computer at the time with 1.1 exaflops of performance.

Improving Computing Memory Performance for Scientific Discovery

Image of a Wigner crystal captured by a high resolution ultra-low temperature scanning tunneling microscope. The periodic sites (blue) form a triangular structure with each consisting of exactly one electron separated by 40 billionths of a meter.

Visualizing an Elusive Quantum Crystal

Left: Scanning tunnel microscopy image of an atomic layer of bismuth/bismuthene (green) on a tin-selenium substrate (black). The inset shows Weyl fermions’ electronic signature. Right: It shows that bismuthene has robust electrical currents at its edges.

Unusual Massless Particle Discovered in a 2D Material

Cells of the green microalga Auxenochlorella protothecoides expressing a red fluorescent protein. These algae accumulate large quantities of oils stored in lipid droplets.

Not Lost in Translation: Algae Show How to Make Two Proteins from One Messenger RNA

These plates show how genetic modifications affect yeasts’ resistance to oxidative stress. Deleting the genes responsible for building cell walls reduced resistance in one species; adding a gene that encodes a key enzyme improved resistance in another.

Machine Learning Reveals Genes That Help Yeasts Resist Stress

A guide RNA strand, in purple, guides CRISPR to a DNA strand. Scientists devised a method to identify genes that can be suppressed to customize microbes for biotechnology applications.

Investigating Cyanobacteria’s Many Paths to Adaptation

A group of researchers in a laboratory, with four men standing up and a man and woman sitting down

Robotic Lab Revolutionizes Plant Bioengineering

Series of five different line graphs indicating how the code matched the experimental data fairly well

Improving Predictions for Fusion Device Transport

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