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Combining Physics and Machine Learning to Analyze Particle Beams in Accelerators A new technique combining physics and machine learning enables scientists to quickly reconstruct details of particle beams without the need for large datasets.
Modeling Storm Clouds Caused by Extreme Wildfires A new study integrates fire processes into an Earth system model to help scientists simulate and better understand the impacts of pyrocumulonimbus clouds.
$Left: X-ray tomography (XRT) image of a miniature sandstone sample. Right: A diffraction microscopy reconstruction of each grain’s compressive stress magnitude and orientation (portrayed as lines with length proportional to magnitude) during deformation.$
Revealing Rock Stresses and Fractures in 3D The evolution of a sandstone’s texture, structure, and stress was measured during deformation for the first time.
Tracing Invisible Spin Currents Scientists directly observed spin wave currents using advanced Resonant X-ray Scattering.

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The QUANT-NET research team has designed a two-level control framework for quantum networks. This two-level control framework and scheduler are being deployed and evaluated in the QUANT-NET testbed.

Building a Flexible Control Framework for Quantum Networks

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The final version of the redesigned drug binds tightly to the main COVID-19 protease, an enzyme the virus needs to multiply. The drug’s structure is effective even against mutated forms that resist other treatments.

Redesigned Hepatitis C Drug Becomes a Powerful New Treatment for COVID-19

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This image shows changes in pressure at the plasma’s outer midplane. It shows how increasing density changes plasma behavior from large potentially damaging instabilities at low density to low-level constant turbulence without bursts at high density.

Protecting Against Large Damaging Energy Bursts in Fusion Energy Devices

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Researchers tested multiple distillable amine-based solvents to see how they performed in pretreatment processes for biomass. They found butylamine was a superior solvent.

A Standout Solvent for Today’s Biorefineries

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Researchers engineered E. coli to use formate as a feedstock to achieve fast growth. This could allow manufacturers to use it to produce precursors for biofuels and bioplastics.

Exploring the Potential of a Formate-Based Bioeconomy

Researchers demonstrated an efficient strain of bacteria for bioproduction that grows on the promising feedstock formate.

Illustration of an undulator’s magnetic field being manipulated to generate ultrafast X-ray pulses. The illustration compares the process to music: Instead of individual notes, researchers played a full melody.

Demonstrating Unprecedented Control of X-ray Pulses

Researchers have used an undulator’s magnetic field to generate and control ultrafast X-ray pulses.

X-ray map of molecular carbonate acquired using scanning transmission X-ray microscopy (yellow). It is overlaid on an inverted bright-field transmission electron microscopy image.

Bennu’s Ancient Brine Sheds Light on Recipe for Life

Using the Advanced Light Source and Molecular Foundry, researchers identified the chemical stew found in samples of the asteroid Bennu.

Images showing mice injected with radioactive antimony. Left panel with TREN-CAM shows how the radioactive antimony will be active longer in the treatment areas. The right panel shows that the antimony without TREN-CAM doesn’t stay in the desired areas.

Progress Towards Unlocking Antimony’s Cancer Treatment Potential

Researchers gain a new understanding of the binding chemistry of radioactive antimony, opening doors for targeted therapy.

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The Uncertainty Toolbox provides a suite of evaluation, visualization, and recalibration functionalities for uncertainty quantification.

Uncertainty Toolbox: A Software Toolbox for Quantifying Uncertainty and More

Scientists used a new method to create 3D metallic and semiconductor nanostructures. The scale bar represents one micrometer. The graphics show how the researchers combined multiple techniques to layer materials on top of a 3D DNA framework "scaffolding."

Building 3D Nanoscale Structures Through DNA-Assembly and Templating

ORNL’s Frontier supercomputer earned the top ranking on the TOP500 list in June 2022, marking it as the world’s fastest computer at the time with 1.1 exaflops of performance.

Improving Computing Memory Performance for Scientific Discovery

Image of a Wigner crystal captured by a high resolution ultra-low temperature scanning tunneling microscope. The periodic sites (blue) form a triangular structure with each consisting of exactly one electron separated by 40 billionths of a meter.

Visualizing an Elusive Quantum Crystal

Left: Scanning tunnel microscopy image of an atomic layer of bismuth/bismuthene (green) on a tin-selenium substrate (black). The inset shows Weyl fermions’ electronic signature. Right: It shows that bismuthene has robust electrical currents at its edges.

Unusual Massless Particle Discovered in a 2D Material

Cells of the green microalga Auxenochlorella protothecoides expressing a red fluorescent protein. These algae accumulate large quantities of oils stored in lipid droplets.

Not Lost in Translation: Algae Show How to Make Two Proteins from One Messenger RNA

These plates show how genetic modifications affect yeasts’ resistance to oxidative stress. Deleting the genes responsible for building cell walls reduced resistance in one species; adding a gene that encodes a key enzyme improved resistance in another.

Machine Learning Reveals Genes That Help Yeasts Resist Stress

A guide RNA strand, in purple, guides CRISPR to a DNA strand. Scientists devised a method to identify genes that can be suppressed to customize microbes for biotechnology applications.

Investigating Cyanobacteria’s Many Paths to Adaptation

A group of researchers in a laboratory, with four men standing up and a man and woman sitting down

Robotic Lab Revolutionizes Plant Bioengineering

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