The Bay Area Site Office (BASO) is an organization within the U.S. Department of Energy's (DOE) Office of Science with responsibility to oversee and administer the Management and Operating (M&O) contracts for the Lawrence Berkeley National Laboratory (LBNL) in Berkeley, California, and the SLAC National Accelerator Laboratory (SLAC) in Menlo Park, California.

LBNL, one of ten Office of Science Laboratories, is a multi-program laboratory managed by the University of California. Its primary mission is to deliver breakthrough science and technology in the areas of Renewable energy; Energy Efficiency; Climate Change and Environmental Science; Chemistry and Physics of Matter and Force in the Universe; Computational Science and Advanced Networking; and Biological Sciences for Human Health and Energy Research.

SLAC is one of ten Office of Science Laboratories and is a multi-program laboratory with a primary mission on delivering breakthrough science and technology in the area of High Energy Physics and Basic Energy Sciences. The SSO is responsible for program implementation, acquisition management, and laboratory stewardship at SLAC. Through its oversight role, the BASO is affecting the safe and efficient operation of LBNL and SLAC while enabling the pursuit of visionary research and development in support of DOE's missions.